The mRNA ‘revolution’ continues.

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NEW MRNA CANCER JAB

Australian authorities say they are taking a ‘significant step’ against childhood brain cancer, with the development of new onshore manufacturing capabilities aimed at producing “personalised” mRNA vaccines – tailored to an individual patient’s tumours.

The initiative – announced this week – positions Australia at the forefront of ‘innovative cancer therapeutics’, bolstering our domestic biotechnology capacity.

The programme centres on the PaedNEO-VAX trial – a world-first clinical study designed to evaluate bespoke mRNA vaccines in children with advanced or treatment-resistant tumours.

The trial, expected to begin later this year, will be rolled out across eight paediatric hospitals in Queensland, South Australia, New South Wales, Victoria, and Western Australia.

Unlike conventional vaccines that prevent infectious diseases, these ‘cancer vaccines’ will aim to ‘train the immune system to recognise and attack malignant cells’.

In this trial, small samples of each participant’s tumour will undergo genomic sequencing to identify unique “neoantigens” – fingerprints on the surface of cancer cells that can be targeted by the immune system.

Once these ‘personalised targets’ are identified, mRNA vaccines will be manufactured to ‘instruct the body’s immune system to wage a precise attack on the tumour’.

All I am hearing is ‘targets’ and ‘attack’ – and I don’t like a technology inside of me that can do that, even if it is supposedly to treat a tumour.

Australia’s biotech firm Southern RNA has been entrusted with the task of producing these tailor-made jabs domestically, supported by Canadian mRNA specialist Providence Therapeutics – which is contributing its proprietary vaccine platform and technical expertise.

Health authorities say this type of local manufacturing capability would mark a significant advance for Australia’s sovereign production of ‘cutting-edge treatments’.

Historically, most mRNA therapeutics and vaccines have been manufactured overseas.

By developing this capacity at home, Australia not only accelerates timelines for manufacturing, but also ensures no chain supply disruptions can occur.

Let’s not forget there was a delay in getting COVID jabs because of this to begin with.

According to the trial’s scientific leads, the ‘personalised vaccines’ are expected to be ready within approximately eight weeks of a child’s enrolment.

Children participating in the study will receive a series of injections, followed by a booster, with clinicians monitoring clinical outcomes over the course of the four-year trial.

Professor Brandon Wainwright, scientific lead of the trial, said that ‘personalised’ mRNA vaccines had already shown “encouraging results” in adult patients with large tumours.

The trial is backed by a combination of government funding, philanthropic support, and private investment. The Australian Government has contributed millions of dollars to enable the research, along with partners such as The University of Queensland and the South Australian Health and Medical Research Institute (SAHMRI).

The future is mRNA, ladies and gentlemen, and every single vaccine will soon become this new form of technology. Able to target and attack inside of one’s body, facilitated by developments in genome editing research.

A ‘revolution’ in health the likes we have only seen in science fiction tales to this point.

Now, it becomes a reality.

MRNA REVOLUTION

Beyond the immediate clinical goals, the project reflects wider strategic efforts to grow Australia’s capacity in advanced biopharmaceutical manufacturing.

Investments in mRNA technology and infrastructure over recent years have laid the groundwork for initiatives like this, which could pave the way for future ‘personalised therapies’ – not only for cancer, but also for a range of other conditions.

COVID jabs were just a surface level introduction to what is coming.

We have already witnessed Australia run head first into this transition, with research hubs, ‘innovative’ jabs already launched, and a future where all jabs are mRNA coded.

Last year, the first ever “breakthrough” mRNA vaccine for foot-and-mouth disease (FMD) was created for livestock, going from a concept to reality in less than 18 months.

“Breakthrough” mRNA jab for Australian livestock unveiled
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Next, the mRNA wave is coming for humans at full force.

In 2024, after two years of construction, Moderna’s ‘world-class’ mRNA manufacturing facility opened in Victoria – with hopes to produce up to 100 million doses per year.

Australia’s first mRNA manufacturing facility officially opens
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The company accompanied this announcement by airing an eerie 90-second TV ad promoting the coming “mRNAge”.

Moderna’s ‘Welcome to the mRNAge’ campaign airs in Australia
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But they are not alone, as stiff competition from other vaccine manufacturers and governments alike rolls in – all looking to cash in on the next wave of jabs for society.

This included the Queensland government, which is looking to rival Victoria’s efforts with their own multi-million dollar research hub dedicated to mRNA research.

QLD joins ‘mRNA revolution’ with plans for new research hub
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CSL, a group that knowingly released millions of contaminated polio vaccines to the Australian public in the 1960s, will also look to being mRNA flu vaccines to Australia.

CSL to bring ‘next-generation’ mRNA flu vaccines to Australia
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The flu has become a major focus of the mRNA tech community, with the U.S. National Institutes of Health (NIH) currently undertaking trials for a “universal” vaccine.

‘Universal’ mRNA flu vaccine clinical trials begin
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This will soon come to Australia, and mRNA will eventually replace traditional vaccines.

The Future of Vaccines | FFT
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There is even a jab coming for urinary tract infections, with the University of Technology Sydney receiving $1.8 million from MRFF’s Global Health Initiative to develop one.

New mRNA jab for urinary infections in the pipeline for Australia
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As I said, every vaccine will be replaced – and new ‘groundbreaking’ techniques will be discovered to supposedly treat even more diseases and ailments.

Diseases and ailments caused by the very same government and health industry to begin with. It’s all a big game, folks.

We shall await to see how this trial pans out.

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